STELLA MARIS COLLEGE
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How Do Prices Work?
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Imagine your body’s cells having a recycling system that suddenly stops working, causing fats and cholesterol to build up continuously inside your vital organs. This is the reality of Lysosomal Acid Lipase Deficiency (LAL-D)—a rare, genetic condition where a missing enzyme turns normal nutrition into a dangerous internal traffic jam.
Historically, LAL-D was studied as two entirely separate conditions. In 1956, Dr. Moshe Wolman identified a severe, rapidly fatal form of the disease in infants (now known as Wolman Disease). Decades later, researchers discovered a milder, late-onset version called Cholesteryl Ester Storage Disease (CESD). It wasn't until advances in genetics in the late 20th century that scientists realized both diseases stem from mutations in the exact same gene (LIPA), resulting in a spectrum of acid lipase deficiency.
LAL-D presents differently depending on how much working enzyme…
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Nice Post